Strattera - Atomoxetine

What is it?

Composition

Strattera contains the active substance atomoxetine, which provides its therapeutic effect. Atomoxetine belongs to the class of selective norepinephrine reuptake inhibitors, affecting the level of this neurotransmitter in the brain.

Each Strattera capsule also contains excipients, which may vary depending on the manufacturer and dosage. Typically, these are:

• Microcrystalline cellulose
• Pregelatinized starch
• Sodium lauryl sulfate
• Talc
• Magnesium stearate

These components help maintain the shape and stability of the drug, ensuring the correct release of atomoxetine in the body.

How to use?

Strattera should be taken strictly as prescribed by a doctor, who will select the optimal dosage depending on the age, body weight and individual characteristics of the patient. The usual starting dosage for adults and children over 6 years old is 0.5 mg per kilogram of body weight per day. The doctor may gradually increase the dose until the maximum therapeutic effect is achieved.

Strattera is taken once or twice a day, depending on the doctors instructions. The drug can be taken both during and on an empty stomach. To achieve the optimal result, it is important to take the capsules regularly at the same time.

1. You must wash down the capsule with a sufficient amount of water, without chewing or opening it.
2. If you miss a dose, do not double the dose the next time, just continue treatment as usual.
3. You should stop taking Strattera only after consulting a doctor, as abrupt cessation may cause unwanted symptoms.

How does it work?

Strattera works by affecting levels of norepinephrine, an important neurotransmitter in the brain that is responsible for regulating attention, impulsivity, and activity. Atomoxetine, the drug’s main active ingredient, is a selective norepinephrine reuptake inhibitor, meaning it prevents this neurotransmitter from being absorbed back into neurons, increasing its levels in the brain.

Increasing norepinephrine levels helps improve focus, reduce hyperactivity, and reduce impulsive behavior. Unlike stimulant medications, Strattera does not directly affect dopamine levels, making it a good option for patients who are sensitive to stimulants. Strattera’s effects develop gradually, usually over a period of weeks, and help provide long-lasting improvements in ADHD symptoms.

Indications

Strattera is used primarily to treat attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults. It is recommended for use in cases where it is necessary to improve concentration, reduce impulsivity, and hyperactivity, thereby improving the quality of life of patients.

The main indications for the use of Strattera include:

• ADHD in children over 6 years of age who require long-term therapy to stabilize behavior and improve academic performance.
• ADHD in adolescents who need symptom control to improve social adaptation and academic performance.
• ADHD in adults who need improved concentration and productivity at work and in everyday life.

The drug can be prescribed both as part of complex therapy and as an independent remedy, depending on the severity of symptoms and individual response to treatment.

Contraindications

Strattera has a number of contraindications, in the presence of which the use of the drug may be unsafe. Before starting treatment, it is necessary to discuss with your doctor all possible risks and health features in order to avoid negative consequences.

Major contraindications include:

• Hypersensitivity or allergic reaction to atomoxetine or any other components of the drug.
• Angle-closure glaucoma, as Strattera may increase intraocular pressure.
• Serious cardiovascular disease, including severe hypertension, tachycardia, and aneurysms, as the drug may worsen the condition.
• Liver disease, as atomoxetine is metabolized in the liver and may cause deterioration of organ function.
• Concomitant use of monoamine oxidase inhibitors (MAOIs), as well as within 14 days of their withdrawal, due to the risk of serious side effects.

It is also recommended to use Strattera with caution in patients with seizure disorders and those with a history of suicidal thoughts or behavior, as the drug may increase the risk of their occurrence.

Side effects

Although Strattera is an effective treatment for ADHD, it can cause a variety of side effects that depend on the individuals response to the drug. In most cases, side effects are minor and go away as the body adapts to the treatment, but it is important to be aware of the possible risks.

The most common side effects include:

• Decreased appetite, which can lead to weight loss, especially in children and adolescents.
• Drowsiness or, conversely, insomnia, especially at the beginning of treatment.
• Nausea and stomach upset, such as constipation or abdominal pain.
• Headaches, which can be intermittent or constant.
• Increased sweating, especially in stressful situations.

Rarely, more serious side effects occur, such as increased blood pressure, increased heart rate, or changes in behavior (for example, increased anxiety or depression). In such cases, you should immediately consult a doctor. Although serious adverse reactions are rare, patients should be closely monitored by their physician, especially when starting treatment with Strattera.