Lisinopril

What is it?

Composition

The composition of the drug Lisinopril is simple, but at the same time highly effective, which makes it an important component in the treatment of cardiovascular diseases. The main active ingredient is lisinopril, which is an ACE inhibitor and is directly responsible for the therapeutic effect on the body. Additional components include various excipients that ensure the stability and digestibility of the drug.

Each ingredient in the drug is selected in such a way as to ensure maximum efficiency and safety during its use. Excipients play a key role in improving absorption and maintaining long-term activity of the main component, which allows the drug to act more purposefully.

• Lisinopril (active ingredient) is an ACE inhibitor.
• Starch is used as a filler.
• Magnesium stearate ensures uniform distribution of the active ingredient.
• Colloidal silicon dioxide promotes formula stability.
• Calcium hydrogen phosphate helps improve drug absorption.

How to use?

Correct use of Lisinopril is key to achieving the best treatment results. The drug is usually taken once a day, preferably at the same time each day to maintain a stable level of the drug in the blood. Lisinopril can be taken regardless of food intake, making it convenient for daily use. It is important to follow your doctors recommendations and not exceed the prescribed dosage to avoid possible side effects.

Before starting treatment, you should carefully read the instructions and consult your doctor, especially if you have chronic diseases or are taking other medications. Changing the dosage or suddenly stopping taking Lisinopril without consulting your doctor may lead to deterioration of your health.

1. Take Lisinopril once a day, at the same time each day.
2. It can be taken with or without food.
3. Do not change the dosage without consulting your doctor.
4. If you miss a dose, take it as soon as possible, but do not double the dose.
5. Check your blood pressure regularly to monitor the effectiveness of treatment.

How does it work?

Lisinopril works by inhibiting angiotensin-converting enzyme (ACE), which reduces the level of angiotensin II in the body. Angiotensin II is a substance that causes vasoconstriction and increases blood pressure. By blocking this process, Lisinopril helps relax and dilate blood vessels, which in turn lowers blood pressure and reduces the load on the heart.

This mechanism of action helps improve blood circulation and relieve the heart, especially in patients with heart failure. Lisinopril also has a protective effect on the kidneys, slowing the progression of their disease in patients with diabetic nephropathy. Thus, the drug not only reduces blood pressure, but also prevents the development of serious complications from the cardiovascular system and kidneys.

Indications

Lisinopril is prescribed for various conditions associated with high blood pressure and heart failure. Its use effectively helps not only to lower blood pressure, but also to prevent the development of severe complications, such as myocardial infarction and stroke. The drug is often prescribed as part of complex therapy when it is necessary to maintain an optimal level of blood pressure.

Lisinopril is especially useful for patients with heart and kidney diseases. It can be used to treat chronic heart failure, as well as to slow the progression of renal failure in patients with diabetes. The drug is also used to improve survival after acute myocardial infarction, reducing the risk of repeated cardiac events.

• Hypertension (high blood pressure).
• Chronic heart failure.
• Prevention of cardiovascular complications after myocardial infarction.
• Diabetic nephropathy (slowing the progression of renal failure).
• Post-infarction therapy to improve survival.

Contraindications

Lisinopril has several important contraindications that must be taken into account before starting treatment. It should not be used in patients with hypersensitivity to lisinopril or other ACE inhibitors. The drug is also contraindicated in people who have previously experienced angioedema (Quinckes edema) associated with taking ACE inhibitors, as there is a high risk of this condition recurring.

In addition, Lisinopril is not recommended for use in the presence of severe renal or hepatic dysfunction, as well as during pregnancy and breastfeeding, as it may cause harm to the fetus or infant. The drug should be used with caution in patients with low blood pressure or in diseases that lead to a decrease in circulating blood volume.

• Hypersensitivity to lisinopril or other ACE inhibitors.
• History of angioedema associated with taking ACE inhibitors.
• Severe renal or hepatic impairment.
• Pregnancy and breastfeeding.
• Conditions associated with decreased circulating blood volume.

Side effects

Like any other medicine, Lisinopril can cause side effects, although most people tolerate it well. The most common side effects are headache, dizziness and feeling tired, which usually occur at the beginning of treatment and disappear as the body adapts to the drug. Dry cough and digestive disorders such as nausea and diarrhea may sometimes occur.

In rare cases, more serious reactions are possible, such as angioedema (swelling of the face, lips, tongue or throat), which requires immediate medical attention. Changes in kidney function and increased potassium levels in the blood are also possible, especially in patients with chronic kidney disease. Therefore, it is important to have regular health checks and report any unusual symptoms to your doctor.

• Headaches and dizziness.
• Feeling tired or weak.
• Dry cough.
• Nausea and indigestion.
• Angioedema (rare, but requires urgent intervention).