Diovan - Valsartan

What is it?

Composition

Diovan contains the active substance valsartan, which is the main component of the drug. This substance belongs to the angiotensin II receptor antagonists, which block the action of this hormone, helping to lower blood pressure. In addition to valsartan, Diovan tablets also contain excipients that ensure the stability and absorption of the drug. Excipients include:

• Colloidal silicon dioxide
• Crospovidone
• Hydroxypropyl methylcellulose
• Iron oxides (yellow, gray-orange and dark purple)

These ingredients help create the shape of the tablet and maintain its effectiveness throughout the shelf life.

How to use?

Diovan should be used strictly according to the doctors recommendations and the instructions. Usually the drug is taken once a day, regardless of food intake. To achieve the maximum effect of treatment, it is important to take the drug at the same time every day. In case of a missed dose, it is recommended to take it as soon as possible, but if it is almost time for the next dose, the missed dose should be skipped and continue taking it according to the usual schedule. Do not take a double dose.

To use the drug, follow the following order:

1. Take the tablets with plenty of water, without chewing them.
2. Follow a regular schedule of administration to maintain a stable level of the drug in the body.
3. Follow any additional recommendations of the doctor regarding diet, physical activity and lifestyle, as they can enhance the effect of Diovan.

It is important to remember that it may take several weeks of treatment to achieve a noticeable effect, especially when treating hypertension

How does it work?

Diovan (valsartan) works by blocking receptors for angiotensin II, a hormone that plays a key role in regulating blood pressure. Angiotensin II narrows blood vessels, which leads to increased pressure and increased workload on the heart. Diovan, by blocking these receptors, prevents the blood vessels from narrowing, which leads to their widening and lower blood pressure. This reduces the workload on the heart and helps improve blood flow, especially in patients with hypertension or heart failure.

The main mechanisms of action of Diovan include:

• Reduction in total peripheral vascular resistance due to vasodilation.
• Reduction in the production of hormones that promote sodium and water retention, which reduces the volume of circulating blood.
• Reduction in the load on the heart muscle, which reduces the risk of complications such as heart failure and stroke.

These effects contribute to a significant reduction in the risk of cardiovascular disease and improve the prognosis in patients with high blood pressure or heart failure.

Indications

Diovan is prescribed for the treatment of various cardiovascular diseases. The main indications include:

• Hypertension: Diovan is used to lower blood pressure in adults and children aged 6 years and older. Lowering blood pressure helps reduce the risk of stroke, heart attack and other complications associated with high blood pressure.
• Heart failure: The drug is used to treat heart failure in adults, reducing the risk of hospitalization and improving overall survival.
• Post-infarction: Diovan helps improve survival after myocardial infarction by reducing the load on the heart and promoting the restoration of cardiac function.

Diovan can be used both as monotherapy and in combination with other antihypertensive drugs, depending on the patients condition and the doctors recommendations.

Contraindications

There are several contraindications for the use of Diovan that need to be considered before starting treatment:

• Hypersensitivity: Diovan should not be used in patients with a known allergy or hypersensitivity to valsartan or any other components of the drug.
• Pregnancy: The drug is strictly contraindicated in pregnancy, especially in the second and third trimesters, as it can cause serious complications, including fetal harm and even death.
• Severe renal impairment: Diovan is contraindicated in patients with severe renal impairment, such as anuria, or in patients undergoing dialysis.

These contraindications are based on the risk of serious side effects and the need to carefully monitor the condition of patients.

Side effects

Diovan, like many medicines, can cause side effects, although not everyone gets them. Some of the most common side effects include:

• Headaches and dizziness: It is common for patients to report headaches or a feeling of lightheadedness, especially during the first few days of taking the drug.
• Digestive problems: These include nausea, diarrhea, and abdominal pain.
• Back and joint pain: Some patients may experience discomfort in the back or joints.
• High levels of potassium in the blood (hyperkalemia): This may manifest as weakness, irregular heartbeat, or a tingling sensation.
• Radiation tract infections: Cold or flu-like symptoms such as cough and fatigue may occur.

It is important to remember that if any serious side effects occur, such as severe dizziness, kidney problems, or symptoms of an allergic reaction, you should contact your doctor immediately.