Depo-Medrol

What is it?

Composition

The composition of Depo-Medrol includes the active substance methylprednisolone acetate and auxiliary components that ensure the stability and effectiveness of the drug. Methylprednisolone acetate is a derivative of prednisolone with the addition of a methyl group, which enhances its anti-inflammatory properties and reduces mineralocorticoid activity. Excipients in the composition of the drug help maintain the stability of the suspension and ensure uniform distribution of the active component upon administration.

How to use?

Depo-Medrol should be used under the supervision of a physician who determines the dosage and route of administration depending on the specific disease and condition of the patient. The drug is administered intramuscularly, intra-articularly or into soft tissues. Before use, shake the bottle thoroughly to ensure homogeneity of the suspension. It is important to follow the doctors recommendations and not exceed the prescribed dose to avoid possible side effects.

How does it work?

The mechanism of action of Depo-Medrol is based on the ability of methylprednisolone to inhibit the release of inflammatory mediators such as prostaglandins and leukotrienes, and to suppress the activity of the immune system. This leads to a reduction in inflammatory reactions, a decrease in swelling and pain, and the suppression of allergic manifestations. Due to its prolonged action, the drug provides a long-term therapeutic effect after a single administration.

Indications

Indications for use of Depo-Medrol include a wide range of diseases:

• Rheumatic diseases, such as rheumatoid arthritis and osteoarthritis.
• Allergic conditions, including severe forms of allergic dermatitis and bronchial asthma.
• Skin diseases, such as psoriasis and eczema.
• Endocrine disorders, such as adrenal insufficiency.
• Hematological diseases, including some forms of anemia and thrombocytopenia.

Contraindications

Contraindications for use of Depo-Medrol:

• Systemic fungal infections.
• Hypersensitivity to methylprednisolone or other components of the drug.
• Injection into infected joints or into unstable joints.
• Severe arterial hypertension or uncontrolled diabetes mellitus.
• Mental illnesses in the acute stage.

Side effects

Side effects of Depo-Medrol may include:

• Increased blood pressure.
• Weight gain and swelling.
• Increased blood sugar.
• Osteoporosis with long-term use.
• Decreased immunity and increased susceptibility to infections.