Clomid - Clomiphene

What is it?

Composition

Clomid contains the active substance clomiphene citrate, which is the main component that provides the therapeutic effect of the drug. Excipients in Clomid help ensure the stability of the drug, its effective absorption and ease of use.

Clomid contains:

• Clomiphene citrate (active substance)
• Lactose
• Magnesium stearate
• Corn starch
• Talc

These components provide the necessary form and structure of the drug, promoting its stability and optimal release of the active substance.

How to use?

Clomid should be taken strictly as prescribed by your doctor, since the treatment regimen may vary depending on the individual characteristics of the body and the purpose of therapy. Treatment usually begins with a low dose, which can be increased if there is no effect.

Recommended regimen for Clomid:

1. The drug is taken orally, usually starting on the 5th day of the menstrual cycle.
2. The course of treatment is usually 5 days, with 50 mg (one tablet) per day.
3. If ovulation does not occur, the dose can be increased to 100 mg per day in the next cycle.

It is important to remember that exceeding the recommended dosage can increase the risk of side effects. Therefore, strictly follow your doctors instructions and do not change the dosage without consulting him.

How does it work?

Clomid works by stimulating ovulation in women with reproductive dysfunction. Its mechanism of action is based on the ability to block estrogen receptors in the hypothalamus, which disrupts the feedback between estrogen and the hypothalamus. This leads to an increase in the level of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are necessary for the maturation of follicles in the ovaries and subsequent ovulation.

Increased production of FSH promotes the growth and maturation of follicles, one of which becomes dominant and ready for ovulation. At the moment of ovulation, the follicle ruptures and the egg is released, which is ready for fertilization. Thus, Clomid helps women with difficulties with ovulation to increase their chances of conception by stimulating natural reproductive processes.

Indications

Clomid is prescribed for a variety of reproductive disorders in women, especially those related to ovulation. It is often used as a first-line treatment for female infertility due to hormonal imbalances.

Indications for Clomid include:

• Anovulatory infertility (lack of ovulation)
• Polycystic ovary syndrome (PCOS)
• Irregular menstrual cycle
• Hypothalamic-pituitary axis disorders
• Unexplained infertility

Clomid may also be used in some cases in men with certain spermatogenesis disorders caused by hormonal imbalances, although this is a less common indication.

Contraindications

Before starting Clomid, it is important to consider the presence of contraindications, as the drug is not suitable for all patients. Some conditions may make the use of Clomid unsafe or ineffective.

Contraindications to the use of Clomid include:

• Hypersensitivity to clomiphene or any of the components of the drug
• Pregnancy
• The presence of ovarian cysts not associated with polycystic ovary disease
• Severe liver dysfunction
• Vision impairment associated with clomiphene
• Uterine bleeding of unknown etiology

In the presence of any of these contraindications, it is necessary to consult a doctor to select an alternative treatment. It is also important to consider that long-term or uncontrolled use of Clomid may increase the risk of side effects and complications.

Side effects

Although Clomid is an effective ovulation inducer, it can cause a number of side effects that are important to consider before starting treatment. Most of these are temporary and go away after the course of treatment, but in some cases, you may need to consult a doctor.

Possible side effects of Clomid include:

• Hot flashes
• Headaches
• Dizziness
• Vision changes, such as blurred or spotted vision
• Mood swings and emotional lability
• Lower abdominal pain or a feeling of heaviness in the pelvis
• Breast swelling

If side effects become severe or do not go away over time, you should consult a doctor. In rare cases, more serious complications, such as ovarian hyperstimulation syndrome, may occur, requiring immediate medical attention.