Champix - Varenicline

What is it?

Composition

The composition of Champix includes the active substance varenicline, which is the main component of the drug and is responsible for its therapeutic effect. One tablet contains either 0.5 mg or 1 mg of varenicline. Excipients in the composition include:

• Microcrystalline cellulose
• Calcium hydrogen phosphate anhydrous
• Sodium croscarmellose
• Magnesium stearate
• Opadry (as part of the tablet shell)

This carefully balanced composition ensures optimal absorption of varenicline and its effect on the body, promoting smoking cessation.

How to use?

Using Champix requires careful adherence to the doctors recommendations to ensure maximum effectiveness and reduce the risk of side effects. Usually, the course begins with a small dosage, which is gradually increased during the first week. This allows the body to adapt to the drug.

1. In the first week, 0.5 mg is taken once a day for the first three days, then 0.5 mg twice a day until the end of the week.
2. From the second week until the end of the course, the dosage is increased to 1 mg twice a day.
3. Tablets should be taken after meals with a sufficient amount of water.
4. It is recommended to start taking the drug 1-2 weeks before the planned date of quitting smoking.

The duration of the course is usually 12 weeks, but it can be extended depending on the individual response to treatment.

How does it work?

Champix works by affecting nicotine receptors in the brain. The active substance varenicline partially stimulates these receptors, which helps reduce the symptoms of nicotine addiction, such as cravings and discomfort when quitting. At the same time, varenicline blocks the receptors, preventing nicotine from consuming cigarettes from activating them. As a result, smoking ceases to bring pleasure, which reduces the motivation to continue smoking.

This dual-action mechanism helps reduce both physical addiction and psychological cravings for smoking, making the process of quitting nicotine more manageable and less stressful for a person.

Indications

Champix is indicated for use to help adults quit smoking who are addicted to nicotine and are ready to stop smoking. The drug is recommended for use as part of a comprehensive program that includes psychological support and motivational counseling. Indications include:

• Desire to reduce or completely quit smoking
• Presence of severe nicotine addiction
• Ineffectiveness of other methods of quitting smoking
• Preference for a drug-based approach to combating smoking

Champix helps to cope with physical addiction to nicotine and makes the process of quitting smoking more comfortable and successful.

Contraindications

There are a number of contraindications to the use of Champix that should be taken into account before starting treatment. This drug is not recommended in the following cases:

• Hypersensitivity or allergy to varenicline or any other components of the drug
• Severe kidney disease, especially if dialysis is required
• Pregnancy and breastfeeding
• Age under 18 years (safety and effectiveness have not been established)
• History of mental disorders such as depression or schizophrenia, without consulting a doctor

Before starting to use Champix, it is important to discuss all possible risks with your doctor, especially if you have chronic diseases or other medical conditions.

Side effects

Like any medicine, Champix can cause side effects. Some are more common than others, but it is important to be aware of possible reactions. Common side effects include:

• Nausea, especially in the first weeks of treatment
• Insomnia or strange dreams
• Headache
• Increased appetite
• Irritability or mood changes

Rarely, more serious side effects may occur, such as mood changes, depression, or aggressive behavior. If any unwanted symptoms occur, you should contact your doctor immediately to assess the need for continued treatment.