Aricept - Donepezil

What is it?

Composition

The composition of Aricept is based on the active ingredient - donepezil, which plays a key role in its therapeutic effect. Each tablet contains a precisely calculated dose of this substance, providing the necessary therapeutic effect. In addition, the drug includes excipients that promote better absorption and stability of the drug.

The drug is available in different forms, such as tablets or film tablets, with a dosage of 5 mg and 10 mg. These dosages are selected depending on the stage of the disease and the patients response to treatment. Donepezil in Aricept is responsible for inhibiting the enzyme acetylcholinesterase, which slows down the destruction of acetylcholine, improving the functioning of the nervous system.

• Donepezil hydrochloride is the active substance.
• Microcrystalline cellulose and corn starch are auxiliary components.
• Hypromellose and magnesium stearate are substances for coating and stabilizing tablets.

How to use?

Aricept should be used strictly according to the doctors recommendations, as improper use may reduce its effectiveness or cause side effects. The tablets are taken orally, usually in the evening, before bedtime, to minimize possible discomfort. The intake does not depend on food, which simplifies the use of the drug in everyday life.

The dosage and treatment regimen depend on the individual needs of the patient and the stage of the disease. Treatment usually begins with a dose of 5 mg per day. The doctor may increase the dosage to 10 mg after 4-6 weeks, if necessary and well tolerated by the patient.

1. Start with a dose of 5 mg per day, taking the tablet in the evening.
2. After 4-6 weeks, evaluate the effectiveness and tolerability of the drug.
3. If necessary, increase the dose to 10 mg per day, following the doctors recommendations.

How does it work?

The mechanism of action of Aricept is based on its ability to inhibit the enzyme acetylcholinesterase, which is responsible for the destruction of acetylcholine, an important neurotransmitter. This process increases the concentration of acetylcholine in the brain, which improves the transmission of nerve impulses and supports cognitive functions.

In Alzheimers disease, the level of acetylcholine decreases, which leads to deterioration of memory, thinking and learning ability. Aricept helps to temporarily slow down these processes, which allows patients to better cope with everyday tasks. However, it is important to understand that the drug does not eliminate the causes of the disease, but has a symptomatic effect.

Indications

Aricept is used to treat mild to moderate cognitive impairment in Alzheimers disease. Its use is aimed at maintaining memory, attention, and other important cognitive functions in patients suffering from this disease. This helps improve the quality of life of both the patient and his loved ones.

Most often, the drug is prescribed in the early stages of the disease, when it is still possible to slow down the progression of symptoms. It is used as part of a complex therapy, which may include both drug therapy and supportive psychological methods.

• Treatment of mild to moderate Alzheimers disease symptoms.
• Maintaining cognitive functions such as memory and attention.
• Increasing the level of social adaptation of patients.

Contraindications

Aricept is contraindicated in a number of cases, which are important to consider before starting treatment. The drug should not be used by people with hypersensitivity to donepezil or any of the excipients of the drug. It is also contraindicated in certain health conditions that may be worsened by its influence.

Particular caution should be exercised in patients with heart disease, pulmonary insufficiency, or a tendency to ulcerative lesions of the gastrointestinal tract. In such cases, the decision to prescribe the drug is made by a doctor, carefully assessing the risks and benefits.

• Allergy to donepezil or excipients in the drug.
• Serious heart disease, such as sick sinus syndrome.
• Tendency to gastrointestinal bleeding.
• Severe forms of asthma or chronic obstructive pulmonary disease.

Side effects

Like any medicine, Aricept can cause side effects. Although most patients tolerate it well, some may experience unpleasant reactions. The most common side effects include digestive upsets such as nausea and diarrhea, as well as headaches and dizziness. These symptoms are usually temporary and go away on their own.

In rare cases, more serious reactions are possible, such as a slow heart rate or muscle cramps. If side effects are severe or last for a long time, you should contact your doctor to adjust your treatment. Regular monitoring by a specialist helps minimize risks.

• Nausea, vomiting, diarrhea.
• Headaches and dizziness.
• Fatigue and weakness.
• Slow heart rate (rare).