Ampicillin - Acillin

What is it?

Composition

Ampicillin contains the active substance Ampicillin trihydrate, which provides its antibacterial action. The main substance is presented in the form of a trihydrate, which allows it to be easily dissolved and absorbed by the body. The drug is available in various forms, such as capsules, tablets and powder for the preparation of an injection solution, which allows you to choose the most convenient method of use.

Ampicillin may also contain excipients, which depend on the form of release of the drug. These substances help improve the stability, absorption and tolerability of the drug.

• Ampicillin trihydrate is the active substance that determines the antibacterial effect of the drug.
• Excipients - ensure ease of use and stability of the drug.

How to use?

Ampicillin is used depending on the severity and type of infection, as well as the age and condition of the patient. The dosage of the drug and the duration of treatment should be determined by the doctor to ensure maximum effectiveness and minimize the risk of side effects. The drug can be used in the form of capsules, tablets or injections.

For adults and children over 12 years old, the standard dose is 250-500 mg every 6 hours. Treatment usually lasts from 5 to 14 days, depending on the type and severity of the infection. The drug should be taken 30 minutes before or 2 hours after meals, with a sufficient amount of water.

1. Take Ampicillin 30 minutes before or 2 hours after meals.
2. The standard dose for adults and children over 12 years old is 250-500 mg every 6 hours.
3. The duration of treatment is from 5 to 14 days, depending on the severity of the infection.

How does it work?

Ampicillin works by inhibiting the synthesis of bacterial cell walls. It blocks enzymes needed to form peptidoglycan, a key component of the bacterial cell wall. Without this structure, bacteria cannot maintain their shape and protect themselves from the external environment, which leads to their destruction and death.

The antibiotic is effective against a wide range of bacteria, including both gram-positive and gram-negative microorganisms. This makes Ampicillin a universal remedy for the treatment of various infections. The drug does not act on viruses, so it is not suitable for the treatment of viral diseases such as colds or flu.

Indications

Ampicillin is used to treat various bacterial infections caused by microorganisms sensitive to it. This drug is prescribed for diseases of the respiratory system, urinary tract, gastrointestinal tract, as well as for infections of the skin and soft tissues. A doctor may recommend Ampicillin for bacterial infections of moderate and mild course, when the causative agent of the disease is confirmed by laboratory tests or is assumed based on the clinical picture.

Ampicillin is most often used to treat the following conditions:

• Infections of the upper and lower respiratory tract (bronchitis, pneumonia, tonsillitis).
• Infections of the urinary tract (cystitis, pyelonephritis).
• Infections of the gastrointestinal tract (salmonellosis, enterocolitis).
• Infections of the skin and soft tissues (boils, abscesses).

Contraindications

Despite the effectiveness of Ampicillin in treating bacterial infections, there are certain conditions in which its use is contraindicated. The drug should not be taken by patients with a known allergy to penicillins or other beta-lactam antibiotics, as it may cause severe allergic reactions, including anaphylactic shock.

Ampicillin is also contraindicated in certain diseases associated with impaired liver and kidney function, as the elimination of the drug from the body may be difficult, which increases the risk of toxicity. Pregnant and lactating women should take Ampicillin only on prescription, since the safety of use in these cases has not been fully established.

• Allergy to penicillins or other beta-lactam antibiotics.
• Severe liver and kidney dysfunction.
• Pregnancy and lactation (only on prescription).

Side effects

Ampicillin, like any antibiotic, can cause side effects, although most patients tolerate it well. Most often, side effects are associated with the gastrointestinal tract. For example, nausea, vomiting, or diarrhea may develop. These symptoms usually disappear after the course of treatment, but sometimes they may require dosage adjustment or a change in drug.

Allergic reactions to Ampicillin also occur, especially in patients with hypersensitivity to penicillins. Allergy can manifest itself in the form of a rash, urticaria, or more serious conditions such as Quinckes edema or anaphylactic shock. In such cases, you should immediately stop taking the drug and consult a doctor.

• Nausea, vomiting, diarrhea.
• Allergic reactions (rash, urticaria, Quinckes edema).
• Dysbacteriosis (disruption of normal intestinal microflora).